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DNA Type 2 Diabetes Test

$349

Does diabetes run in your family? Take this DNA test to understand your genetic risk for type 2 diabetes.

  • Includes variants that influence glucose levels, fat metabolism, insulin production and response to insulin
  • 70% chance of developing type 2 diabetes when both parents have the disease
  • Private and confidential online results
  • Painless sample collection

Collection method:  Buccal swab

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Detailed Description

Type 2 diabetes is a metabolic disorder that disrupts the body’s normal glucose and insulin balance. It is generally associated with unhealthy lifestyles and extra body weight, but genetic variations can also increase your risk, regardless of your lifestyle.

Glucose is the primary source of energy used by the cells in our bodies. The levels of this simple sugar are regulated by the hormone insulin, produced by the beta cells of the pancreas. People with type 2 diabetes do not make sufficient amounts of insulin, therefore have consistently high blood sugar levels.

With a simple mouth swab you can find out whether you have inherited DNA changes that increase your risk of type 2 diabetes. 

The Genetics

Genetic variations can affect our glucose and insulin levels, sensitivity to dietary fatty acids, and the way our body responds to insulin, resulting in increased risk of type 2 diabetes. Knowledge of genetic variants that increase your risk of type 2 diabetes allows you to make lifestyle changes today, to reduce your risk of this debilitating condition.

Variants Tested

Gene(s) Tested

Effect

ACC2

Reduced response to insulin

ADCY5

Inhibited secretion of insulin

FABP2, FTO

Increased uptake of saturated fats

ADIPOQ, CRY2, FADS1, G6PC2, GLUT2, MTNR1B, PROX1, TCF7L2

Increased fasting glucose levels

GCKR

Reduced fasting glucose levels

GCK, HNF4A

Reduced pancreatic beta cell function

GLIS3, IRS1, SLC30A8

Disrupted insulin production/signalling/storage

SHBG

Increased sex hormone binding globulin

MADD

Impaired proinsulin-to-insulin conversion

SOD2

Increased reactive oxygen species

HIF1A

Resistance to hypoxia

Discover More

How many diabetes risk factors do you have?

  • Genetic variation
  • Family history of type 2 diabetes
  • Obesity and fat accumulation (around the abdomen)
  • Lack of physical exercise
  • Ethnicity (Africans and American Indians have a higher risk)
  • Prediabetes – elevated blood sugar
  • Gestational diabetes
  • Polycystic ovarian syndrome

How It Works

Order your test

Choose the test that matches your need from our large array of tests. The kit will be delivered to your doorstep. There is no need to leave the comfort of your home.

Collect your sample

Register and activate your test. Collect your sample. Return your sample to our lab as soon as possible, using the prepaid envelope included in the kit.

Quality guarantee

Your sample will be tested as soon as it arrives in our lab. Your results will be available through our secure online platform.